Next-Generation Sequencing (NGS)
NGS analyses many DNA or RNA regions in parallel. Depending on the assay, it can examine a focused gene panel, the protein-coding regions of the genome, or broader genomic regions.
Clinical Applications
- Hereditary-condition and inherited cancer-risk assessment.
- Tumour profiling for selected diagnostic, prognostic, or treatment-related biomarkers.
- Evaluation of complex or undiagnosed genetic conditions using broader assays.
Selecting an Assay
A focused panel may provide deeper coverage for a defined question, while exome or genome sequencing can examine a broader range of genes. The best option depends on the phenotype, specimen, family history, and clinical purpose.
Results and Limitations
NGS does not detect every type of genetic change. Coverage, variant classes, specimen quality, tumour content, and interpretation criteria vary by assay. Results may include pathogenic variants, benign variants, or variants of uncertain significance.
NGS at Jaipur Molecular Lab
Contact our team to confirm the available panel, accepted sample types, reportable variant classes, and expected reporting timeline.
This information is for general education and does not replace medical advice. Test selection and interpretation should be discussed with a qualified clinician or genetic counsellor.