HER2 Testing

HER2 testing evaluates the status of the ERBB2 (HER2) gene or protein in tumour tissue. The result can help clinicians classify a tumour and determine whether HER2-directed treatment may be relevant.

How HER2 Is Assessed

Immunohistochemistry (IHC): Assesses HER2 protein expression in tumour cells.
In situ hybridisation, including FISH: Assesses HER2 gene amplification and may be used for selected or equivocal cases according to tumour-specific guidance.

Specimen Requirements

Testing generally requires suitable formalin-fixed, paraffin-embedded tumour tissue. Accurate interpretation depends on specimen handling, tumour content, the validated assay, and the tumour type.

Understanding the Report

HER2 scoring systems and treatment thresholds vary by tumour type. Results should be reviewed with the pathology report and current clinical guidelines by the treating oncology team.

Testing at Jaipur Molecular Lab

Contact our team to confirm the available HER2 method, specimen requirements, and expected reporting timeline.

Ask About HER2 Testing

This information is for general education and does not replace medical advice. Test selection and interpretation should be discussed with the treating clinician and pathologist.