What is NGS?
NGS involves sequencing, or “reading,” the building blocks of DNA and RNA, called nucleotides. These sequences form the blueprints for all living organisms. By analyzing them, researchers can uncover valuable information about health, disease, and biological processes.
Why is NGS important?
NGS transforms the way we study genetics. It helps:
- Detect genetic mutations that cause diseases.
- Identify specific changes in cancer cells to guide treatment.
- Track pathogens like viruses or bacteria through their genetic material.
- Discover new genes and understand their functions.
How does NGS work?
The NGS process consists of several steps:
- Extracting DNA or RNA: First, genetic material is taken from a sample, such as blood or tissue.
- Fragmenting the genetic material: The DNA or RNA is broken into smaller pieces.
- Preparing the library: Scientists add specific adapters to the fragments, enabling the sequencing machine to read them.
- Sequencing the fragments: The machine decodes millions of nucleotide fragments at the same time, providing their exact order (A, T, G, C for DNA; A, U, G, C for RNA).
- Analyzing the data: Advanced software pieces the sequences together and generates a complete genetic profile.
Key features of NGS:
NGS offers several advantages:
- High throughput: It can analyze millions of fragments simultaneously.
- Speed and accuracy: Results are available much faster than older methods, with fewer errors.
- Cost-effectiveness: The technology has become more affordable over time.
Applications of NGS:
NGS drives breakthroughs in many areas:
- In healthcare, it helps diagnose genetic disorders, guide personalized treatments, and monitor infectious diseases.
- In research, it reveals how genes contribute to diseases or influence behaviors.
- In agriculture, it improves crops, tracks plant diseases, and supports sustainable farming.
NGS at Jaipur Molecular Lab
Jaipur Molecular Lab offers state-of-the-art Next-Generation Sequencing (NGS) services, bringing advanced genetic testing to healthcare, research, and diagnostics. With cutting-edge technology and a skilled team, the lab provides fast, accurate, and cost-effective solutions tailored to diverse needs.
Applications of NGS at Jaipur Molecular Lab
Clinical Diagnostics & Other Tests:
- Detect genetic disorders with high sensitivity.
- Guide cancer treatments through tumor mutation analysis.
- Perform non-invasive prenatal testing (NIPT).
- Whole Genome Sequencing (WGS).
- Whole Exome Sequencing (WES).
- BRCA 1 & BRCA 2
- Solid Tumor Panel
- HRR & HRD
In conclusion, NGS (Next Generation Sequencing services at Jaipur Molecular Lab)has revolutionized genetic science by making it easier to decode complex genetic information. Its speed, accuracy, and broad applications make it a powerful tool for advancing medicine, research, and agriculture.