1p/19q Co-deletion Testing
A 1p/19q co-deletion is the combined loss of genetic material from the short arm of chromosome 1 and the long arm of chromosome 19. In the appropriate clinical and pathological context, whole-arm 1p/19q co-deletion is an important molecular feature used in the integrated classification of oligodendroglioma.
Why the Test Is Requested
- To support classification of a diffuse glioma together with histology and other molecular findings, including IDH status.
- To provide information that may contribute to prognosis and treatment planning.
- To help distinguish tumour entities that can appear similar under the microscope.
Testing and Interpretation
Testing is performed on suitable tumour tissue. Available methods may include fluorescence in situ hybridisation (FISH), copy-number analysis, or sequencing-based approaches. Method-specific limitations matter—for example, some assays may detect a limited-region deletion rather than confirm whole-arm loss.
A result should be interpreted alongside histopathology, IDH status, tumour content, and the technical scope of the assay. A positive or negative finding should not be considered in isolation.
Testing at Jaipur Molecular Lab
Contact our team to confirm the accepted specimen type, assay method, tissue requirements, and expected reporting timeline.
This information is for general education and does not replace medical advice. Test selection and interpretation should be discussed with the treating clinician and pathologist.